The average bus between Buffalo and Salisbury takes 16h 41m and the fastest bus takes 15h 10m. The bus service runs several times per day from Buffalo to Salisbury. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Buffalo and Salisbury. The earliest departure is at 3:30 AM at night, and the last departure from Buffalo is at 11:00 PM which arrives into Salisbury at 4:40 PM. All services require a transfer at Newark Penn Station and take an average of 16h 41m. The schedules shown below are for the next available departures.


15h 10m • 2 changes
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16h 40m • 2 changes
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17h 40m • 2 changes


15h 10m • 2 changes
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16h 40m • 2 changes
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17h 40m • 2 changes


15h 10m • 2 changes
Arrives next day


16h 40m • 2 changes
Arrives next day


17h 40m • 2 changes


17h 10m • 2 changes
Arrives next day


16h 40m • 2 changes
Arrives next day


17h 40m • 2 changes


17h 10m • 2 changes
Arrives next day


16h 40m • 2 changes
Arrives next day


17h 40m • 2 changes
Want to know about travelling from Buffalo to Salisbury? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Buffalo to Salisbury. However, there are services departing from Buffalo station and arriving at Salisbury station via Newark Penn Station station. The journey, including transfers, takes approximately 16h 41m.
Buffalo to Salisbury bus services, operated by Flixbus USA, depart from Buffalo station.
Buffalo to Salisbury bus services, operated by Flixbus USA, arrive at Salisbury, MD station.
Book your Buffalo to Salisbury bus tickets online with Flixbus USA, BayRunner Shuttle and Greyhound USA.
The distance between Buffalo and Salisbury is 574.2 km. The road distance is 1,126 km.
You can take a bus from Buffalo to Salisbury, MD via Newark Penn Station, Baltimore Downtown Bus Station, and Baltimore, MD - Greyhound Bus Terminal Downtown in around 15h 9m.