The average bus between Buffalo and Wayne takes 9h 37m and the fastest bus takes 8h 56m. The bus service runs several times per day from Buffalo to Wayne. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Buffalo and Wayne. The earliest departure is at 6:00 AM in the morning, and the last departure from Buffalo is at 11:15 PM which arrives into Wayne at 8:38 AM. All services require a transfer at New York and take an average of 9h 37m. The schedules shown below are for the next available departures.

9h 12m • 1 change

9h 12m • 1 change

8h 56m • 1 change
Arrives next day

9h 23m • 1 change
Arrives next day

17h 18m • 1 change
Arrives next day

9h 23m • 1 change

9h 12m • 1 change

9h 12m • 1 change

8h 56m • 1 change
Arrives next day

9h 23m • 1 change
Want to know about travelling from Buffalo to Wayne? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Buffalo to Wayne. However, there are services departing from Buffalo station and arriving at Wayne station via New York. The journey, including transfers, takes approximately 9h 37m.
Buffalo to Wayne bus services, operated by Trailways, depart from Buffalo station.
Buffalo to Wayne bus services, operated by Trailways, arrive at Mothers Park & Ride Rt 23 North station.
The distance between Buffalo and Wayne is 438.7 km. The road distance is 834 km.
You can take a bus from Buffalo to Mothers Park & Ride Rt 23 North via New York and Port Authority Bus Terminal in around 9h 2m.