Buffalo to Wayne Buses

Buffalo to Wayne buses

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Trip Overview

The average bus between Buffalo and Wayne takes 15h 53m and the fastest bus takes 11h 53m. The bus service runs several times per day from Buffalo to Wayne. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h 53m
Duration: 502 mi
Distance: $110
Average price: 4 times a day
Frequency

Bus

best

Take the bus from Buffalo to Newark Penn Stationbus FlixBus N2686 / ...
Take the bus from Newark Penn Station to Philadelphia Bus Stationbus FlixBus 2601 / ...

13h 12m

$82–138

Buffalo to Wayne bus times

Buses run 4 times a day between Buffalo and Wayne. The earliest departure is at 3:30 AM at night, and the last departure from Buffalo is at 11:00 PM which arrives into Wayne at 10:53 AM. All services require a transfer at Newark Penn Station and take an average of 15h 53m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

5:30 AM → 6:56 PM
13h 26m • 3 changes
10:30 AM → 5:42 AM
Arrives next day
19h 12m • 3 changes
5:20 PM → 7:55 AM
Arrives next day
14h 35m • 3 changes
11:00 PM → 10:53 AM
Arrives next day
11h 53m • 3 changes

Departing Tuesday, November 10, 2026

3:30 AM → 4:53 PM
13h 23m • 3 changes
5:30 AM → 6:56 PM
13h 26m • 3 changes
10:30 AM → 5:42 AM
Arrives next day
19h 12m • 3 changes
5:20 PM → 7:55 AM
Arrives next day
14h 35m • 3 changes
Show more

Departing Wednesday, November 11, 2026

3:30 AM → 4:53 PM
13h 23m • 3 changes
9:00 AM → 5:42 AM
Arrives next day
20h 42m • 3 changes
5:20 PM → 7:55 AM
Arrives next day
14h 35m • 3 changes
11:00 PM → 1:57 PM
Arrives next day
14h 57m • 3 changes

Departing Thursday, November 12, 2026

10:30 AM → 5:42 AM
Arrives next day
19h 12m • 3 changes
5:20 PM → 7:55 AM
Arrives next day
14h 35m • 3 changes
11:00 PM → 1:57 PM
Arrives next day
14h 57m • 3 changes

Departing Friday, November 13, 2026

5:30 AM → 6:56 PM
13h 26m • 3 changes
10:30 AM → 6:40 AM
Arrives next day
20h 10m • 3 changes
5:20 PM → 8:40 AM
Arrives next day
15h 20m • 3 changes
11:00 PM → 2:45 PM
Arrives next day
15h 45m • 3 changes

Departing Saturday, November 14, 2026

3:30 AM → 4:45 PM
13h 15m • 3 changes
5:30 AM → 6:44 PM
13h 14m • 3 changes

Frequently asked questions

Want to know about travelling from Buffalo to Wayne? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Trip Overview

Bus