Rome2Rio

Buffalo to Wytheville buses

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Trip Overview

The bus between Buffalo and Wytheville takes 30h 10m. The bus runs, on average, 6 times per week from Buffalo to Wytheville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

30h 10m
Duration
595 mi
Distance
$133
Average price
6 times a week
Frequency

Buffalo to Wytheville bus times

Buses run 6 times a week between Buffalo and Wytheville. The service departs Buffalo at 2:00 PM in the afternoon, which arrives into Wytheville at 20:10:00. All services require a transfer at Akron and take an average of 30h 10m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    TrailwaysGreyhound USAVirginia Breeze30h 10m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    TrailwaysGreyhound USAVirginia Breeze30h 10m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    TrailwaysGreyhound USAVirginia Breeze30h 10m • 2 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    TrailwaysGreyhound USAVirginia Breeze30h 10m • 2 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    TrailwaysGreyhound USAVirginia Breeze30h 10m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    TrailwaysGreyhound USAVirginia Breeze30h 10m • 2 changes

Frequently asked questions

Want to know about travelling from Buffalo to Wytheville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to Wytheville.ExpandLaunch map view
  • Distance: 595.2 mi
  • Duration: 30h 10m

What companies run services between Buffalo, NY, USA and Wytheville, VA, USA?

You can take a bus from Buffalo to Wytheville via Akron, Charleston, and Wytheville in around 13h 14m.

Operators