The average bus between Caltagirone and Messina takes 3h 51m and the fastest bus takes 3h 5m. The bus service runs several times per day from Caltagirone to Messina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Caltagirone and Messina. The earliest departure is at 6:50 AM in the morning, and the last departure from Caltagirone is at 5:45 PM which arrives into Messina at 9:25 PM. All services require a transfer, and take on average 3h 51m. The schedules shown below are for the next available departures.

3h 10m • 1 change

3h 5m • 1 change

5h 20m • 1 change

3h 5m • 1 change

3h 10m • 1 change

3h 5m • 1 change

8h 5m • 1 change

3h 5m • 1 change

3h 10m • 1 change

3h 5m • 1 change

8h 5m • 1 change

3h 5m • 1 change

3h 10m • 1 change

3h 5m • 1 change

5h 20m • 1 change

3h 5m • 1 change
Want to know about travelling from Caltagirone to Messina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Caltagirone to Messina. However, there are services departing from Caltagirone station and arriving at Messina station via Catania Central Bus Station station. The journey, including transfers, takes approximately 3h 51m.
Caltagirone to Messina bus services, operated by Azienda Siciliana Trasporti, depart from Caltagirone Bus Station.
Caltagirone to Messina bus services, operated by Azienda Siciliana Trasporti, arrive at Messina Piazza della Repubblica station.
The distance between Caltagirone and Messina is 140.1 km. The road distance is 164 km.
You can take a bus from Caltagirone Bus Station to Messina Piazza della Repubblica via Catania Central Bus Station in around 3h 35m.