The average bus between Cambridge and Penzance takes 12h 55m and the fastest bus takes 11h 45m. The bus service runs several times per day from Cambridge to Penzance. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Cambridge and Penzance. The earliest departure is at 5:45 AM in the morning, and the last departure from Cambridge is at 6:15 PM which arrives into Penzance at 7:05 AM. All services require a transfer, and take on average 12h 55m. The schedules shown below are for the next available departures.

12h 55m • 1 change
12h • 1 change
14h 15m • 1 changeArrives next day

12h 50m • 1 change
12h 55m • 1 change
12h • 1 change
14h 15m • 1 changeArrives next day

12h 50m • 1 change
12h 55m • 1 change
12h 30m • 1 change
14h 30m • 1 changeArrives next day

12h 50m • 1 change
12h • 1 change
11h 45m • 1 change
14h • 1 changeArrives next day

12h 50m • 1 changeWant to know about travelling from Cambridge to Penzance? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cambridge to Penzance. However, there are services departing from Cambridge station and arriving at Penzance station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 12h 55m.
Cambridge to Penzance bus services, operated by National Express, depart from Parkside station.
Cambridge to Penzance bus services, operated by National Express, arrive at Bus Station.
Book your Cambridge to Penzance bus tickets online with National Express.
The distance between Cambridge and Penzance is 457 km. The road distance is 605 km.
You can take a bus from Parkside to Bus Station via Heathrow Central Bus Station in around 11h 20m.