The average bus between Cambridge and South Yarmouth takes 3h 45m and the fastest bus takes 2h 20m. The bus service runs several times per day from Cambridge to South Yarmouth. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Cambridge and South Yarmouth. The earliest departure is at 8:00 AM in the morning, and the last departure from Cambridge is at 8:00 PM which arrives into South Yarmouth at 6:50 AM. All services require a transfer at Hyannis and take an average of 3h 45m. The schedules shown below are for the next available departures.

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Want to know about travelling from Cambridge to South Yarmouth? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cambridge to South Yarmouth. However, there are services departing from Cambridge station and arriving at South Yarmouth station via Hyannis. The journey, including transfers, takes approximately 3h 45m.
Cambridge to South Yarmouth bus services, operated by Peter Pan Bus Lines, depart from Boston station.
Cambridge to South Yarmouth bus services, operated by Peter Pan Bus Lines, arrive at Hyannis station.
The distance between Cambridge and South Yarmouth is 109.5 km. The road distance is 126 km.
Peter Pan Bus Lines operates a bus from Boston to Hyannis every 3 hours. Tickets cost $15–40 and the journey takes 1h 40m.