The average bus between Cancún and Guadalajara takes 35h 6m and the fastest bus takes 34h. The bus service runs several times per day from Cancún to Guadalajara. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Cancún and Guadalajara. The earliest departure is at 10:30 AM in the morning, and the last departure from Cancún is at 6:30 PM which arrives into Guadalajara at 5:30 AM. All services require a transfer, and take on average 35h 6m. The schedules shown below are for the next available departures.
Arrives next day

34h 20m • 1 change
Arrives +2 days

33h • 1 change
Arrives +2 days

35h • 1 change
Arrives next day

34h 20m • 1 change
Arrives +2 days

33h • 1 change
Arrives +2 days

35h • 1 change
Arrives next day

34h 20m • 1 change
Arrives +2 days

33h • 1 change
Arrives +2 days

35h • 1 change
Want to know about travelling from Cancún to Guadalajara? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cancún to Guadalajara. However, there are services departing from Cancún station and arriving at Guadalajara station via Terminal Central de Autobuses del Norte. The journey, including transfers, takes approximately 35h 6m.
Cancún to Guadalajara bus services, operated by ADO, depart from Terminal de Autobuses ADO Cancún station.
Cancún to Guadalajara bus services, operated by ADO, arrive at Nueva Central Camionera de Guadalajara Mod 1 station.
Book your Cancún to Guadalajara bus tickets online with ADO and Primera Plus.
The distance between Cancún and Guadalajara is 1,718.6 km. The road distance is 2,194 km.
You can take a bus from Terminal de Autobuses ADO Cancún to Nueva Central Camionera de Guadalajara Mod 1 via Terminal Central de Autobuses del Norte in around 34h 27m.