Rome2Rio

Cancún to Guadalajara buses

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Trip Overview

The average bus between Cancún and Guadalajara takes 35h 6m and the fastest bus takes 34h. The bus service runs several times per day from Cancún to Guadalajara. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

35h 6m
Duration
2,194 km
Distance
$4,493
Average price
3 times a day
Frequency

Cancún to Guadalajara bus times

Buses run 3 times a day between Cancún and Guadalajara. The earliest departure is at 10:30 AM in the morning, and the last departure from Cancún is at 6:30 PM which arrives into Guadalajara at 5:30 AM. All services require a transfer, and take on average 35h 6m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    ADOPrimera Plus34h • 1 change
  •  → 

    Arrives +2 days

    ADOPrimera Plus36h • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    ADOPrimera Plus35h 20m • 1 change
  •  → 

    Arrives +2 days

    ADOPrimera Plus34h • 1 change
  •  → 

    Arrives +2 days

    ADOPrimera Plus36h • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    ADOPrimera Plus35h 20m • 1 change
  •  → 

    Arrives +2 days

    ADOPrimera Plus34h • 1 change
  •  → 

    Arrives +2 days

    ADOPrimera Plus36h • 1 change

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    ADOPrimera Plus35h 20m • 1 change
  •  → 

    Arrives +2 days

    ADOPrimera Plus34h • 1 change
  •  → 

    Arrives +2 days

    ADOPrimera Plus36h • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    ADOPrimera Plus35h 20m • 1 change
  •  → 

    Arrives +2 days

    ADOPrimera Plus34h • 1 change
  •  → 

    Arrives +2 days

    ADOPrimera Plus36h • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    ADOPrimera Plus35h 20m • 1 change
  •  → 

    Arrives +2 days

    ADOPrimera Plus34h • 1 change
  •  → 

    Arrives +2 days

    ADOPrimera Plus36h • 1 change

Frequently asked questions

Want to know about travelling from Cancún to Guadalajara? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Cancún to Guadalajara.ExpandLaunch map view
  • Distance: 2,193.9 km
  • Duration: 35h 6m

What companies run services between Cancún, Mexico and Guadalajara, Mexico?

You can take a bus from Terminal de Autobuses ADO Cancún to Nueva Central Camionera de Guadalajara Mod 1 via Terminal Central de Autobuses del Norte in around 34h 27m.

Operators