The average bus between Canton and Syracuse takes 12h 14m and the fastest bus takes 8h 28m. The bus service runs several times per day from Canton to Syracuse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Canton and Syracuse. The earliest departure is at 10:15 AM in the morning, and the last departure from Canton is at 7:22 PM which arrives into Syracuse at 1:40 PM. All services require a transfer at Mattapan and take an average of 12h 14m. The schedules shown below are for the next available departures.



8h 38m • 3 changes



8h 28m • 3 changes
Arrives next day



18h 21m • 3 changes



8h 40m • 3 changes



8h 30m • 3 changes
Arrives next day



18h 18m • 3 changes
Want to know about travelling from Canton to Syracuse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Canton to Syracuse. However, there are services departing from Canton station and arriving at Syracuse station via Syracuse Bus Station station. The journey, including transfers, takes approximately 12h 14m.
Canton to Syracuse bus services, operated by MBTA, depart from Boston station.
Canton to Syracuse bus services, operated by MBTA, arrive at Syracuse Bus Station.
The distance between Canton and Syracuse is 421.2 km. The road distance is 536 km.
Greyhound USA operates a bus from Boston to Syracuse Bus Station twice daily. Tickets cost $45–90 and the journey takes 6h 25m. Flixbus USA also services this route 3 times a week.