The average bus between Canton of Lucerne and Milan takes 4h 8m and the fastest bus takes 3h 46m. The bus service runs several times per day from Canton of Lucerne to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Canton of Lucerne and Milan. The earliest departure is at 5:15 AM in the morning, and the last departure from Canton of Lucerne is at 11:30 PM which arrives into Milan at 6:18 AM. All services require a transfer at via omodeo via cechov and take an average of 4h 8m. The schedules shown below are for the next available departures.

5h 46m • 1 change

5h 51m • 1 change
Arrives next day

6h 48m • 1 change

5h 51m • 1 change

5h 49m • 1 change
Arrives next day

6h 48m • 1 change
Want to know about travelling from Canton of Lucerne to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Canton of Lucerne to Milan. However, there are services departing from Canton of Lucerne station and arriving at Milan station via Milan. The journey, including transfers, takes approximately 4h 8m.
Canton of Lucerne to Milan bus services, operated by FlixBus, depart from Luzern station.
Canton of Lucerne to Milan bus services, operated by FlixBus, arrive at Milan station.
The distance between Canton of Lucerne and Milan is 197 km. The road distance is 241 km.
FlixBus operates a bus from Luzern to Milan 3 times a day. Tickets cost €20–35 and the journey takes 3h 20m. RegioJet also services this route 3 times a week.