The average bus between Cape Cod and Portsmouth takes 7h 16m and the fastest bus takes 5h 4m. The bus service runs several times per day from Cape Cod to Portsmouth. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Cape Cod and Portsmouth. The earliest departure is at 2:46 PM in the afternoon, and the last departure from Cape Cod is at 6:46 PM which arrives into Portsmouth at 6:10 AM. All services require a transfer at Hyannis Transportation Center and take an average of 7h 16m. The schedules shown below are for the next available departures.


5h 4m • 2 changes


6h 4m • 2 changes
Arrives next day


11h 24m • 2 changes


5h 4m • 2 changes


6h 4m • 2 changes
Arrives next day


11h 24m • 2 changes


5h 4m • 2 changes


6h 4m • 2 changes
Arrives next day


11h 24m • 2 changes


5h 4m • 2 changes


6h 4m • 2 changes
Arrives next day


11h 24m • 2 changes
Want to know about travelling from Cape Cod to Portsmouth? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cape Cod to Portsmouth. However, there are services departing from Cape Cod station and arriving at Portsmouth station via South Station Transp. Ctr station. The journey, including transfers, takes approximately 7h 16m.
Cape Cod to Portsmouth bus services, operated by Cape Cod Regional Transit Authority, depart from Hyannis Transportation Center station.
Cape Cod to Portsmouth bus services, operated by Cape Cod Regional Transit Authority, arrive at Portsmouth Bus Stop station.
The distance between Cape Cod and Portsmouth is 162 km. The road distance is 217 km.
You can take a bus from Town Hall Lawton Bus Shelter to Portsmouth Bus Stop via Hyannis Transportation Center, South Station Transp. Ctr, and Boston in around 4h 32m.