Rome2Rio

Cape Coral to Buffalo buses

Find Transport to Buffalo

View schedule

Trip Overview

The average bus between Cape Coral and Buffalo takes 47h 57m and the fastest bus takes 47h 49m. The bus runs, on average, 3 times per week from Cape Coral to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

47h 57m
Duration
1,716 mi
Distance
$333
Average price
3 times a week
Frequency

Cape Coral to Buffalo bus times

Buses run 3 times a week between Cape Coral and Buffalo. The earliest departure is at 5:10 PM in the evening, and the last departure from Cape Coral is at 5:11 PM which arrives into Buffalo at 5:25 PM. All services require a transfer at Fort Myers Bus Stop and take an average of 47h 57m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    Lee County TransitFlixbus USAFlixbus USAFlixbus USA47h 49m • 3 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    Lee County TransitFlixbus USAFlixbus USAFlixbus USA47h 49m • 3 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +2 days

    Lee County TransitFlixbus USAFlixbus USAGreyhound USA2d • 3 changes

Frequently asked questions

Want to know about travelling from Cape Coral to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Cape Coral to Buffalo.ExpandLaunch map view
  • Distance: 1,716.4 mi
  • Duration: 47h 57m

What companies run services between Cape Coral, FL, USA and Buffalo, NY, USA?

You can take a bus from Cc Pwky @ Vincennes St to Buffalo via Fort Myers Bus Stop, Orlando Bus Station, and Newark Penn Station in around 37h 13m.

Operators