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Cape Coral to Missouri buses

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Trip Overview

The average bus between Cape Coral and Missouri takes 41h 33m and the fastest bus takes 41h 30m. The bus runs, on average, 5 times per week from Cape Coral to Missouri. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

41h 33m
Duration
1,477 mi
Distance
$302
Average price
5 times a week
Frequency

Cape Coral to Missouri bus times

Buses run 5 times a week between Cape Coral and Missouri. The earliest departure is at 10:56 AM in the morning, and the last departure from Cape Coral is at 11:14 AM which arrives into Missouri at 3:45 AM. All services require a transfer at Fort Myers Bus Stop and take an average of 41h 33m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    Lee County TransitFlixbus USAFlixbus USAGreyhound USAGreyhound USA41h 30m • 4 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    Lee County TransitFlixbus USAFlixbus USAGreyhound USAGreyhound USA41h 30m • 4 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    Lee County TransitFlixbus USAFlixbus USAGreyhound USAGreyhound USA41h 30m • 4 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +2 days

    Lee County TransitFlixbus USAFlixbus USAGreyhound USAGreyhound USA41h 48m • 4 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives +2 days

    Lee County TransitFlixbus USAFlixbus USAGreyhound USAGreyhound USA41h 30m • 4 changes

Frequently asked questions

Want to know about travelling from Cape Coral to Missouri? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Cape Coral to Missouri.ExpandLaunch map view
  • Distance: 1,477 mi
  • Duration: 41h 33m

What companies run services between Cape Coral, FL, USA and Missouri, USA?

You can take a bus from Cc Pwky @ Vincennes St to Kansas City Bus Station via Fort Myers Bus Stop, Tampa Bus Station, Atlanta Bus Station, and St Louis Bus Station in around 32h 40m.

Operators