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Cape Coral to Myrtle Beach buses

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Trip Overview

The average bus between Cape Coral and Myrtle Beach takes 42h 24m and the fastest bus takes 42h 23m. The bus runs, on average, 5 times per week from Cape Coral to Myrtle Beach. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

42h 24m
Duration
929 mi
Distance
$178
Average price
5 times a week
Frequency

Cape Coral to Myrtle Beach bus times

Buses run 5 times a week between Cape Coral and Myrtle Beach. The earliest departure is at 5:10 PM in the evening, and the last departure from Cape Coral is at 5:11 PM which arrives into Myrtle Beach at 11:35 AM. All services require a transfer at Fort Myers Bus Stop and take an average of 42h 24m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    Lee County TransitFlixbus USAFlixbus USAGreyhound USA42h 24m • 3 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    Lee County TransitFlixbus USAFlixbus USAGreyhound USA42h 24m • 3 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    Lee County TransitFlixbus USAFlixbus USAGreyhound USA42h 24m • 3 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    Lee County TransitFlixbus USAFlixbus USAGreyhound USA42h 24m • 3 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +2 days

    Lee County TransitFlixbus USAFlixbus USAGreyhound USA42h 23m • 3 changes

Frequently asked questions

Want to know about travelling from Cape Coral to Myrtle Beach? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Cape Coral to Myrtle Beach.ExpandLaunch map view
  • Distance: 928.6 mi
  • Duration: 42h 24m

What companies run services between Cape Coral, FL, USA and Myrtle Beach, SC, USA?

You can take a bus from Cc Pwky @ Vincennes St to Myrtle Beach Bus Station via Fort Myers Bus Stop, Orlando Bus Station, and Fayetteville Bus Station in around 22h 5m.

Operators