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Cardinal Hotel St. Peter, Rome to Florence buses

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Trip Overview

The average bus between Cardinal Hotel St. Peter, Rome and Florence takes 4h 38m and the fastest bus takes 4h 5m. There is a bus service every few hours from Cardinal Hotel St. Peter, Rome to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 38m
Duration
290 km
Distance
€38
Average price
Hourly
Frequency

Line 490 bus, bus

best
  1. Take the bus from Emo/Di Bartolo to Roma, Autostazione Tiburtinabus bus 490 / ...
  2. Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus bus 510 / ...
4h 51m
€16–52

Cardinal Hotel St. Peter, Rome to Florence bus times

Buses run hourly between Cardinal Hotel St. Peter, Rome and Florence. The earliest departure is at 5:25 AM in the morning, and the last departure from Cardinal Hotel St. Peter, Rome is at 9:45 PM which arrives into Florence at 2:35 AM. All services require a transfer at Leone Xiii/Pio Xi and take an average of 4h 38m. The schedules shown below are for the next available departures.

Departing Monday, October 12, 2026

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    ATAC S.p.A. Azienda per la mobilitàATAC S.p.A. Azienda per la mobilitàFlixBus4h 49m • 2 changes

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    ATAC S.p.A. Azienda per la mobilitàATAC S.p.A. Azienda per la mobilitàFlixBus4h 19m • 2 changes

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    ATAC S.p.A. Azienda per la mobilitàATAC S.p.A. Azienda per la mobilitàFlixBus4h 41m • 2 changes

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    ATAC S.p.A. Azienda per la mobilitàATAC S.p.A. Azienda per la mobilitàFlixBus4h 45m • 2 changes
  • Show more

Departing Tuesday, October 13, 2026

  •  → 

    ATAC S.p.A. Azienda per la mobilitàATAC S.p.A. Azienda per la mobilitàFlixBus4h 49m • 2 changes

  •  → 

    ATAC S.p.A. Azienda per la mobilitàATAC S.p.A. Azienda per la mobilitàFlixBus4h 19m • 2 changes

  •  → 

    ATAC S.p.A. Azienda per la mobilitàATAC S.p.A. Azienda per la mobilitàFlixBus4h 41m • 2 changes

  •  → 

    ATAC S.p.A. Azienda per la mobilitàATAC S.p.A. Azienda per la mobilitàFlixBus4h 45m • 2 changes
  • Show more

Departing Wednesday, October 14, 2026

  •  → 

    ATAC S.p.A. Azienda per la mobilitàATAC S.p.A. Azienda per la mobilitàFlixBus4h 19m • 2 changes

  •  → 

    ATAC S.p.A. Azienda per la mobilitàATAC S.p.A. Azienda per la mobilitàFlixBus4h 41m • 2 changes

  •  → 

    ATAC S.p.A. Azienda per la mobilitàATAC S.p.A. Azienda per la mobilitàFlixBus4h 45m • 2 changes

  •  → 

    ATAC S.p.A. Azienda per la mobilitàATAC S.p.A. Azienda per la mobilitàFlixBus4h 24m • 2 changes
  • Show more

Frequently asked questions

Want to know about travelling from Cardinal Hotel St. Peter, Rome to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Cardinal Hotel St. Peter, Rome to Florence.ExpandLaunch map view
  • Distance: 290 km
  • Duration: 4h 38m

What companies run services between Cardinal Hotel St. Peter, Rome, Italy and Florence, Italy?

You can take a vehicle from Cardinal Hotel St. Peter, Rome to Florence Villa Constanza Bus Station via Leone Xiii/Pio Xi, Anastasio Ii/Pieralice, Emo/Di Bartolo, and Roma, Autostazione Tiburtina in around 4h 51m.

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