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Carlisle to St. Louis buses

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Trip Overview

The average bus between Carlisle and St. Louis takes 22h 43m and the fastest bus takes 20h 39m. The bus service runs several times per day from Carlisle to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 43m
Duration
825 mi
Distance
$142
Average price
Twice daily
Frequency

Bus (Greyhound)

best
  1. Take the bus from Harrisburg Bus Station to St Louis Bus Stationbus bus Greyhound US0421
20h 6m
$122–242

Carlisle to St. Louis bus times

Buses run twice daily between Carlisle and St. Louis. The earliest departure is at 12:06 PM in the afternoon, and the last departure from Carlisle is at 7:06 PM which arrives into St. Louis at 7:45 AM. All services require a transfer at Market Square Transfer Center and take an average of 22h 43m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Carlisle to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Carlisle to St. Louis.ExpandLaunch map view
  • Distance: 824.5 mi
  • Duration: 22h 43m

What companies run services between Carlisle, PA, USA and St. Louis, MO, USA?

Greyhound USA operates a bus from Harrisburg Bus Station to St Louis Bus Station twice daily. Tickets cost $120–240 and the journey takes 18h 5m.

Operators