The average bus between Cartagena and Mérida takes 12h 56m and the fastest bus takes 11h 55m. The bus service runs several times per day from Cartagena to Mérida. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Cartagena and Mérida. The earliest departure is at 9:15 AM in the morning, and the last departure from Cartagena is at 9:00 PM which arrives into Mérida at 10:50 AM. All services require a transfer, and take on average 12h 56m. The schedules shown below are for the next available departures.

12h 10m • 1 change
Arrives next day

11h 55m • 1 change
Arrives next day

13h 50m • 1 change

12h 10m • 1 change
Arrives next day

11h 55m • 1 change
Arrives next day

13h 50m • 1 change

12h 10m • 1 change
Arrives next day

11h 55m • 1 change
Arrives next day

13h 50m • 1 change

12h 10m • 1 change
Arrives next day

11h 55m • 1 change
Arrives next day

13h 50m • 1 change

12h 10m • 1 change
Arrives next day

11h 55m • 1 change
Arrives next day

13h 50m • 1 change
Want to know about travelling from Cartagena to Mérida? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cartagena to Mérida. However, there are services departing from Cartagena station and arriving at Mérida station via Sevilla, Estación de Autobuses (Plaza de Armas). The journey, including transfers, takes approximately 12h 56m.
Cartagena to Mérida bus services, operated by ALSA, depart from Cartagena station.
Cartagena to Mérida bus services, operated by ALSA, arrive at Merida station.
Book your Cartagena to Mérida bus tickets online with ALSA.
The distance between Cartagena and Mérida is 489.9 km. The road distance is 752 km.
You can take a bus from Cartagena to Merida via Sevilla, Estación de Autobuses (Plaza de Armas) in around 11h 10m.