The average bus between Cartagena and San Sebastián de los Reyes takes 6h 45m and the fastest bus takes 5h 55m. The bus service runs several times per day from Cartagena to San Sebastián de los Reyes. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Cartagena and San Sebastián de los Reyes. The earliest departure is at 7:15 AM in the morning, and the last departure from Cartagena is at 11:15 PM which arrives into San Sebastián de los Reyes at 6:25 AM. All services require a transfer at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) and take an average of 6h 45m. The schedules shown below are for the next available departures.

6h 25m • 1 change

7h 40m • 1 change

5h 55m • 1 change
Arrives next day

7h 40m • 1 change

6h 25m • 1 change

7h 40m • 1 change

5h 55m • 1 change
Arrives next day

7h 10m • 1 change

5h 57m • 1 change

7h 27m • 1 change

6h 12m • 1 change
Arrives next day

7h 10m • 1 change

5h 57m • 1 change

7h 27m • 1 change

6h 12m • 1 change
Arrives next day

7h 10m • 1 change
Want to know about travelling from Cartagena to San Sebastián de los Reyes? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cartagena to San Sebastián de los Reyes. However, there are services departing from Cartagena station and arriving at San Sebastián de los Reyes station via Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid). The journey, including transfers, takes approximately 6h 45m.
Cartagena to San Sebastián de los Reyes bus services, operated by ALSA, depart from Cartagena station.
Cartagena to San Sebastián de los Reyes bus services, operated by ALSA, arrive at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) station.
The distance between Cartagena and San Sebastián de los Reyes is 399.5 km. The road distance is 475 km.
ALSA operates a bus from Cartagena to Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) 3 times a day. Tickets cost €35–60 and the journey takes 5h 40m.