The average bus between Cary and Winston-Salem takes 4h 27m and the fastest bus takes 2h 40m. The bus service runs several times per day from Cary to Winston-Salem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Cary and Winston-Salem. The earliest departure is at 1:00 PM in the afternoon, and the last departure from Cary is at 10:45 PM which arrives into Winston-Salem at 6:45 AM. All services require a transfer at Regional Transit Center and take an average of 4h 27m. The schedules shown below are for the next available departures.


3h 25m • 2 changes


2h 40m • 2 changes
Arrives next day


8h • 2 changes


3h 25m • 2 changes


2h 40m • 2 changes
Arrives next day


8h • 2 changes


3h 25m • 2 changes


2h 40m • 2 changes
Arrives next day


8h • 2 changes
Want to know about travelling from Cary to Winston-Salem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cary to Winston-Salem. However, there are services departing from Cary station and arriving at Winston-Salem station via Durham Station station. The journey, including transfers, takes approximately 4h 27m.
Cary to Winston-Salem bus services, operated by Go Triangle, depart from Regional Transit Center station.
Cary to Winston-Salem bus services, operated by Go Triangle, arrive at Winston Salem(Trans Center) station.
The distance between Cary and Winston-Salem is 136.1 km. The road distance is 165 km.
You can take a bus from Cary Depot to Winston Salem(Trans Center) via Regional Transit Center, Durham Station, and Durham in around 3h 49m.