The average bus between Catania and Sambuca takes 18h 30m and the fastest bus takes 15h 24m. The bus service runs several times per day from Catania to Sambuca. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Catania and Sambuca. The earliest departure is at 9:25 AM in the morning, and the last departure from Catania is at 6:40 PM which arrives into Sambuca at 10:04 AM. All services require a transfer at Siena and take an average of 18h 30m. The schedules shown below are for the next available departures.
Arrives next day


22h • 2 changes
Arrives next day


15h 24m • 2 changes
Arrives next day


22h • 2 changes
Arrives next day


15h 26m • 2 changes
Want to know about travelling from Catania to Sambuca? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Catania to Sambuca. However, there are services departing from Catania station and arriving at Sambuca station via Siena. The journey, including transfers, takes approximately 18h 30m.
Catania to Sambuca bus services, operated by FlixBus, depart from Catania station.
Catania to Sambuca bus services, operated by FlixBus, arrive at Siena station.
The distance between Catania and Sambuca is 749.7 km. The road distance is 1,049 km.
FlixBus operates a bus from Catania to Siena twice daily. Tickets cost €75–130 and the journey takes 13h 5m. Itabus S.p.A. also services this route once daily.