The average bus between Central Islip and East Setauket takes 1h 25m and the fastest bus takes 59 min. There is an hourly bus service from Central Islip to East Setauket. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Central Islip and East Setauket. The earliest departure is at 7:10 AM in the morning, and the last departure from Central Islip is at 10:16 PM which arrives into East Setauket at 6:47 AM. All services require a transfer, and take on average 1h 25m. The schedules shown below are for the next available departures.

59 min • 1 change

59 min • 1 change

59 min • 1 change

59 min • 1 change

1h 35m • 1 change

1h 35m • 1 change

1h 35m • 1 change

1h 35m • 1 change

1h 42m • 1 change

1h 42m • 1 change

1h 42m • 1 change

1h 42m • 1 change
Want to know about travelling from Central Islip to East Setauket? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Central Islip to East Setauket. However, there are services departing from Central Islip station and arriving at East Setauket station via Smith Haven Mall. The journey, including transfers, takes approximately 1h 25m.
Central Islip to East Setauket bus services, operated by Suffolk County Transit, depart from E Suffolk Ave/Carleton Ave station.
Central Islip to East Setauket bus services, operated by Suffolk County Transit, arrive at NYS 25A/Old Town Road station.
The distance between Central Islip and East Setauket is 18.6 km. The road distance is 25 km.
You can take a bus from E Suffolk Ave/Carleton Ave to NYS 25A/Old Town Road via Smith Haven Mall in around 1h 21m.