The average bus between Central Milton Keynes and Manchester takes 3h 53m and the fastest bus takes 3h 5m. There is a bus service every few hours from Central Milton Keynes to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Central Milton Keynes and Manchester. The earliest departure is at 12:10 AM at night, and the last departure from Central Milton Keynes is at 11:30 PM which arrives into Manchester at 6:15 AM. All services require a transfer, and take on average 3h 53m. The schedules shown below are for the next available departures.

6h 5m • 1 change

6h 9m • 1 change

3h 29m • 1 change

3h 22m • 1 change

6h 5m • 1 change

3h 32m • 1 change

3h 42m • 1 change

3h 32m • 1 change

3h 22m • 1 change

3h 22m • 1 change

3h 32m • 1 change

4h 17m • 1 change
Want to know about travelling from Central Milton Keynes to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Central Milton Keynes to Manchester. However, there are services departing from Central Milton Keynes station and arriving at Manchester station via Manchester Central Coach Station station. The journey, including transfers, takes approximately 3h 53m.
Central Milton Keynes to Manchester bus services, operated by Stagecoach East, depart from Milton Keynes Coachway station.
Central Milton Keynes to Manchester bus services, operated by Stagecoach East, arrive at Manchester Central Coach Station.
The distance between Central Milton Keynes and Manchester is 188.5 km. The road distance is 252 km.
National Express operates a bus from Milton Keynes Coachway to Manchester Central Coach Station every 30 minutes. Tickets cost £29–70 and the journey takes 3h 55m.