The average bus between Centre-Val de Loire and Lyon takes 7h 6m and the fastest bus takes 6h 33m. The bus service runs several times per day from Centre-Val de Loire to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Centre-Val de Loire and Lyon. The earliest departure is at 10:24 AM in the morning, and the last departure from Centre-Val de Loire is at 11:12 PM which arrives into Lyon at 5:45 AM. All services require a transfer at Vaucanson and take an average of 7h 6m. The schedules shown below are for the next available departures.

7h 40m • 1 change
Arrives next day

7h 4m • 1 change
Arrives next day

6h 33m • 1 change

7h 40m • 1 change
Arrives next day

7h 4m • 1 change
Arrives next day

6h 33m • 1 change

7h 51m • 1 change
Arrives next day

7h • 1 change
Arrives next day

6h 37m • 1 change
Want to know about travelling from Centre-Val de Loire to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Centre-Val de Loire to Lyon. However, there are services departing from Centre-Val de Loire station and arriving at Lyon station via Lyon. The journey, including transfers, takes approximately 7h 6m.
Centre-Val de Loire to Lyon bus services, operated by Filbleu - Tours, depart from Tours station.
Centre-Val de Loire to Lyon bus services, operated by Filbleu - Tours, arrive at Lyon station.
The distance between Centre-Val de Loire and Lyon is 310.8 km. The road distance is 514 km.
FlixBus operates a bus from Tours to Lyon 6 times a week. Tickets cost €40–75 and the journey takes 6h 25m. BlaBlaCar Bus also services this route once daily.