Rome2Rio

Charleston to Duke University buses

Find Transport to Duke University

View schedule

Trip Overview

The average bus between Charleston and Duke University takes 16h 44m and the fastest bus takes 12h 57m. The bus runs, on average, 6 times per week from Charleston to Duke University. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

16h 44m
Duration
355 mi
Distance
$80
Average price
6 times a week
Frequency

Charleston to Duke University bus times

Buses run 6 times a week between Charleston and Duke University. The earliest departure is at 9:35 AM in the morning, and the last departure from Charleston is at 7:14 PM which arrives into Duke University at 6:12 AM. All services require a transfer at N. Charleston SuperStop and take an average of 16h 44m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

  •  → 

    CARTACARTAGreyhound USAFlixbus USAGoDurham13h 7m • 4 changes

Departing Thursday, November 5, 2026

  •  → 

    CARTACARTAGreyhound USAFlixbus USAGoDurham13h 7m • 4 changes

Departing Friday, November 6, 2026

  •  → 

    CARTACARTAGreyhound USAFlixbus USAGoDurham13h 7m • 4 changes

Departing Saturday, November 7, 2026

  •  → 

    CARTACARTAGreyhound USAFlixbus USAGoDurham12h 57m • 4 changes
  •  → 

    Arrives +2 days

    CARTACARTAGreyhound USAGreyhound USAGoDurham34h 58m • 4 changes

Departing Monday, November 9, 2026

  •  → 

    CARTACARTAGreyhound USAFlixbus USAGoDurham13h 7m • 4 changes

Frequently asked questions

Want to know about travelling from Charleston to Duke University? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Charleston to Duke University.ExpandLaunch map view
  • Distance: 355.3 mi
  • Duration: 16h 44m

What companies run services between Charleston, SC, USA and Duke University, NC, USA?

Greyhound USA operates a bus from Charleston Bus Station to Raleigh Bus Station once daily. Tickets cost $55–90 and the journey takes 7h 15m.

Operators