Rome2Rio

Charleston to Durham buses

Find Transport to Durham

View schedule

Trip Overview

The average bus between Charleston and Durham takes 13h 33m and the fastest bus takes 12h 15m. The bus runs, on average, 6 times per week from Charleston to Durham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

13h 33m
Duration
353 mi
Distance
$79
Average price
6 times a week
Frequency

Charleston to Durham bus times

Buses run 6 times a week between Charleston and Durham. The earliest departure is at 9:35 AM in the morning, and the last departure from Charleston is at 9:45 AM which arrives into Durham at 10:00 PM. All services require a transfer at N. Charleston SuperStop and take an average of 13h 33m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

  •  → 

    CARTACARTAGreyhound USAFlixbus USA12h 25m • 3 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    CARTACARTAGreyhound USAGreyhound USA15h 55m • 3 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    CARTACARTAGreyhound USAGreyhound USA15h 55m • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    CARTACARTAGreyhound USAFlixbus USA12h 25m • 3 changes

Departing Friday, November 13, 2026

  •  → 

    CARTACARTAGreyhound USAFlixbus USA12h 25m • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    CARTACARTAGreyhound USAFlixbus USA12h 15m • 3 changes

Frequently asked questions

Want to know about travelling from Charleston to Durham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Charleston to Durham.ExpandLaunch map view
  • Distance: 352.8 mi
  • Duration: 13h 33m

What companies run services between Charleston, SC, USA and Durham, NC, USA?

Greyhound USA operates a bus from Charleston Bus Station to Raleigh Bus Station once daily. Tickets cost $55–85 and the journey takes 7h 15m.

Operators