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Charleston to Frederick buses

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Trip Overview

The average bus between Charleston and Frederick takes 25h 16m and the fastest bus takes 22h 45m. The bus runs, on average, 6 times per week from Charleston to Frederick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

25h 16m
Duration
634 mi
Distance
$139
Average price
6 times a week
Frequency

Charleston to Frederick bus times

Buses run 6 times a week between Charleston and Frederick. The earliest departure is at 9:35 AM in the morning, and the last departure from Charleston is at 7:14 PM which arrives into Frederick at 8:30 AM. All services require a transfer at N. Charleston SuperStop and take an average of 25h 16m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    CARTACARTAGreyhound USAFlixbus USAGreyhound USA37h 16m • 4 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    CARTACARTAGreyhound USAFlixbus USAGreyhound USA22h 55m • 4 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    CARTACARTAGreyhound USAFlixbus USAGreyhound USA22h 55m • 4 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    CARTACARTAGreyhound USAFlixbus USAGreyhound USA22h 55m • 4 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    CARTACARTAGreyhound USAFlixbus USAGreyhound USA22h 55m • 4 changes

Frequently asked questions

Want to know about travelling from Charleston to Frederick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Charleston to Frederick.ExpandLaunch map view
  • Distance: 633.8 mi
  • Duration: 25h 16m

What companies run services between Charleston, SC, USA and Frederick, MD, USA?

You can take a bus from Mary St / Meeting St to Frederick Bus Station via N. Charleston SuperStop, North Charleston Transit Center, Charleston Bus Station, Raleigh Bus Station, and Washington Union Station in around 17h 1m.

Operators