The average bus between Charlestown and Hyannis takes 2h 35m and the fastest bus takes 2h 15m. There is a bus service every few hours from Charlestown to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Charlestown and Hyannis. The earliest departure is at 6:00 AM in the morning, and the last departure from Charlestown is at 7:30 PM which arrives into Hyannis at 10:35 PM. All services require a transfer at Downtown Crossing and take an average of 2h 35m. The schedules shown below are for the next available departures.

2h 15m • 1 change

2h 16m • 1 change

2h 35m • 1 change

2h 40m • 1 change

2h 15m • 1 change

2h 16m • 1 change

2h 35m • 1 change

2h 40m • 1 change

2h 15m • 1 change

2h 16m • 1 change

2h 35m • 1 change

2h 40m • 1 change
Want to know about travelling from Charlestown to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Charlestown to Hyannis. However, there are services departing from Charlestown station and arriving at Hyannis station via Hyannis Transportation Center. The journey, including transfers, takes approximately 2h 35m.
Charlestown to Hyannis bus services, operated by MBTA, depart from Boston South Station.
Charlestown to Hyannis bus services, operated by MBTA, arrive at Hyannis Transportation Center station.
The distance between Charlestown and Hyannis is 103.1 km. The road distance is 118 km.
Peter Pan Bus Lines operates a bus from Boston South Station to Hyannis Transportation Center every 3 hours. Tickets cost $15–40 and the journey takes 1h 35m.