Rome2Rio

Charlotte to Florida Keys buses

Find Transport to Florida Keys

View schedule

Trip Overview

The average bus between Charlotte and Florida Keys takes 2d 4h and the fastest bus takes 2d 3h. The bus runs, on average, 4 times per week from Charlotte to Florida Keys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 4h
Duration
1,054 mi
Distance
$210
Average price
4 times a week
Frequency

Charlotte to Florida Keys bus times

Buses run 4 times a week between Charlotte and Florida Keys. The service departs Charlotte at 8:25 AM in the morning, which arrives into Florida Keys at 12:15:00. All services require a transfer at Fayetteville Bus Station and take an average of 2d 4h. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAGreyhound USAKey West Transit2d 4h • 3 changes

Departing Saturday, October 31, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAGreyhound USAKey West Transit2d 4h • 3 changes

Departing Monday, November 2, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAGreyhound USAKey West Transit2d 3h • 3 changes

Departing Tuesday, November 3, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAGreyhound USAKey West Transit2d 3h • 3 changes

Frequently asked questions

Want to know about travelling from Charlotte to Florida Keys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Charlotte to Florida Keys.ExpandLaunch map view
  • Distance: 1,053.5 mi
  • Duration: 2d 4h

What companies run services between Charlotte, NC, USA and Florida Keys, FL, USA?

You can take a bus from Charlotte Bus Station to Florida Keys via Fayetteville Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 25h 40m.

Operators