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Charlotte to Louisville buses

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Trip Overview

The average bus between Charlotte and Louisville takes 17h 22m and the fastest bus takes 15h 40m. The bus service runs several times per day from Charlotte to Louisville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

17h 22m
Duration
665 mi
Distance
$139
Average price
Twice daily
Frequency

Charlotte to Louisville bus times

Buses run twice daily between Charlotte and Louisville. The earliest departure is at 11:15 AM in the morning, and the last departure from Charlotte is at 12:55 PM which arrives into Louisville at 8:00 AM. All services require a transfer at Atlanta Downtown and take an average of 17h 22m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Flixbus USAGreyhound USAAmtrak Thruway15h 40m • 2 changes
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    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway19h 5m • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USAAmtrak Thruway15h 40m • 2 changes
  •  → 

    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway19h 5m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Flixbus USAGreyhound USAAmtrak Thruway15h 40m • 2 changes
  •  → 

    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway19h 5m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USAAmtrak Thruway15h 40m • 2 changes
  •  → 

    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway19h 5m • 2 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Flixbus USAGreyhound USAAmtrak Thruway15h 40m • 2 changes
  •  → 

    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway19h 5m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USAAmtrak Thruway15h 40m • 2 changes
  •  → 

    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway19h 5m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USAAmtrak Thruway15h 40m • 2 changes

Frequently asked questions

Want to know about travelling from Charlotte to Louisville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Charlotte to Louisville.ExpandLaunch map view
  • Distance: 665.5 mi
  • Duration: 17h 22m

What companies run services between Charlotte, NC, USA and Louisville, KY, USA?

You can take a bus from Charlotte Bus Station to Louisville, KY via Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, and Nashville in around 14h 14m.

Operators