Rome2Rio

Chicago Bus Station to Indianapolis buses

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Trip Overview

The average bus between Chicago Bus Station and Indianapolis takes 3h 57m and the fastest bus takes 3h 5m. The bus service runs several times per day from Chicago Bus Station to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 57m
Duration
183 mi
Distance
$40
Average price
Every 2 hours
Frequency

Chicago Bus Station to Indianapolis bus times

Buses run every 2 hours between Chicago Bus Station and Indianapolis. The earliest departure is at 6:10 AM in the morning, and the last departure from Chicago Bus Station is at 10:50 PM which arrives into Indianapolis at 4:15 AM. All services run direct with no transfers required, and take on average 3h 57m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    bus bus 3h 50m • Direct
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    Arrives next day

    bus bus 4h 25m • Direct

Departing Thursday, November 12, 2026

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    bus bus 3h 35m • Direct
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    bus bus 3h 45m • Direct
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    bus bus 4h 10m • Direct
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    bus bus 3h 30m • Direct
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Departing Friday, November 13, 2026

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    bus bus 3h 35m • Direct
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    bus bus 3h 50m • Direct
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    bus bus 3h 45m • Direct
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    bus bus 4h 10m • Direct
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Departing Saturday, November 14, 2026

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    bus bus 3h 35m • Direct
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    bus bus 3h 50m • Direct
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    bus bus 3h 45m • Direct
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    bus bus 4h 10m • Direct
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Departing Sunday, November 15, 2026

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    bus bus 3h 35m • Direct
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    bus bus 3h 50m • Direct
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    bus bus 3h 45m • Direct
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    bus bus 4h 10m • Direct
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Departing Monday, November 16, 2026

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    bus bus 3h 35m • Direct
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    bus bus 3h 50m • Direct
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    bus bus 3h 45m • Direct
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    bus bus 4h 10m • Direct
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Departing Tuesday, November 17, 2026

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    bus bus 3h 35m • Direct
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    bus bus 3h 50m • Direct
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    bus bus 3h 45m • Direct
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    bus bus 4h 10m • Direct
  • Show more

Frequently asked questions

Want to know about travelling from Chicago Bus Station to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago Bus Station to Indianapolis.ExpandLaunch map view
  • Distance: 182.5 mi
  • Duration: 3h 57m

What companies run services between Chicago Bus Station, IL, USA and Indianapolis, IN, USA?

Flixbus USA operates a bus from Chicago Bus Station to Indianapolis every 4 hours. Tickets cost $29–45 and the journey takes 3h 45m. Greyhound USA also services this route 5 times a day.

Operators