Rome2Rio

Chicago Union Station to Buffalo buses

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Trip Overview

The bus between Chicago Union Station and Buffalo takes 12h 35m. There is at least one bus per day from Chicago Union Station to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 35m
Duration
540 mi
Distance
$98
Average price
Once daily
Frequency

Chicago Union Station to Buffalo bus times

Buses run once daily between Chicago Union Station and Buffalo. The service departs Chicago Union Station at 10:05 AM in the morning, which arrives into Buffalo at 22:40:00. All services require a transfer at Chicago and take an average of 12h 35m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Barons BusBarons Bus12h 35m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Barons BusBarons Bus12h 35m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Barons BusBarons Bus12h 35m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Barons BusBarons Bus12h 35m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Barons BusBarons Bus12h 35m • 1 change

Departing Monday, November 16, 2026

  •  → 

    Barons BusBarons Bus12h 35m • 1 change

Frequently asked questions

Want to know about travelling from Chicago Union Station to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago Union Station to Buffalo.ExpandLaunch map view
  • Distance: 540.3 mi
  • Duration: 12h 35m

What companies run services between Chicago Union Station, IL, USA and Buffalo, NY, USA?

You can take a vehicle from Chicago Union Station to Buffalo via Chicago and Cleveland in around 11h 14m.

Operators