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Chicago to Clayton buses

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Trip Overview

The average bus between Chicago and Clayton takes 7h 41m and the fastest bus takes 7h 21m. The bus service runs several times per day from Chicago to Clayton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h 41m
Duration
327 mi
Distance
$62
Average price
3 times a day
Frequency

Bus (Flixbus)

best
  1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
7h 11m
$52–86

Chicago to Clayton bus times

Buses run 3 times a day between Chicago and Clayton. The earliest departure is at 12:15 AM at night, and the last departure from Chicago is at 5:05 PM which arrives into Clayton at 1:00 AM. All services require a transfer at St Louis Bus Station and take an average of 7h 41m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Chicago to Clayton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago to Clayton.ExpandLaunch map view
  • Distance: 326.8 mi
  • Duration: 7h 41m

What companies run services between Chicago, IL, USA and Clayton, MO, USA?

Flixbus USA operates a bus from Chicago Bus Station to St Louis Bus Station twice daily. Tickets cost $50–85 and the journey takes 5h 55m.

Operators