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Chicago to Des Moines buses

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Trip Overview

The bus between Chicago and Des Moines takes 2d 11h. The bus runs, on average, once a week from Chicago to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 11h
Duration
2,424 mi
Distance
$512
Average price
Once a week
Frequency

Chicago to Des Moines bus times

Buses run once a week between Chicago and Des Moines. The service departs Chicago at 12:25 PM in the afternoon, which arrives into Des Moines at 21:27:16. All services require a transfer at Denver Union Station and take an average of 2d 11h. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAKing County MetroKing County Metro2d 11h • 3 changes

Frequently asked questions

Want to know about travelling from Chicago to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago to Des Moines.ExpandLaunch map view
  • Distance: 2,424.5 mi
  • Duration: 2d 11h

What companies run services between Chicago, IL, USA and Des Moines, WA, USA?

You can take a bus from Chicago Bus Station to S 216th St & Wesley Terrace Entrance via Denver Union Station, Seattle Bus Station, SODO Busway & S Royal Brougham Way, and Andover Park W & Baker Blvd - Bay 1 in around 2d 4h.

Operators