Rome2Rio

Chicago to Lafayette buses

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Trip Overview

The average bus between Chicago and Lafayette takes 24h 45m and the fastest bus takes 22h 30m. The bus runs, on average, 5 times per week from Chicago to Lafayette. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

24h 45m
Duration
1,111 mi
Distance
$225
Average price
5 times a week
Frequency

Chicago to Lafayette bus times

Buses run 5 times a week between Chicago and Lafayette. The earliest departure is at 9:45 AM in the morning, and the last departure from Chicago is at 10:30 PM which arrives into Lafayette at 8:15 AM. All services require a transfer, and take on average 24h 45m. The schedules shown below are for the next available departures.

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USA22h 30m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USA22h 30m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USA22h 30m • 1 change

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USA22h 30m • 1 change
  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USA33h 45m • 1 change

Frequently asked questions

Want to know about travelling from Chicago to Lafayette? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago to Lafayette.ExpandLaunch map view
  • Distance: 1,111.5 mi
  • Duration: 24h 45m

What companies run services between Chicago, IL, USA and Lafayette, LA, USA?

You can take a bus from Chicago Bus Station to Lafayette via Memphis Bus Station in around 21h 15m.

Operators