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Chicago to San Luis Obispo buses

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Trip Overview

The bus between Chicago and San Luis Obispo takes 2d 21h. The bus runs, on average, 3 times per week from Chicago to San Luis Obispo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 21h
Duration
2,408 mi
Distance
$505
Average price
3 times a week
Frequency

Chicago to San Luis Obispo bus times

Buses run 3 times a week between Chicago and San Luis Obispo. The service departs Chicago at 5:05 PM in the evening, which arrives into San Luis Obispo at 13:00:00. All services require a transfer at St Louis Bus Station and take an average of 2d 21h. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Arrives +3 days

    Flixbus USAGreyhound USAFlixbus USA2d 21h • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +3 days

    Flixbus USAGreyhound USAFlixbus USA2d 21h • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +3 days

    Flixbus USAGreyhound USAFlixbus USA2d 21h • 2 changes

Frequently asked questions

Want to know about travelling from Chicago to San Luis Obispo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago to San Luis Obispo.ExpandLaunch map view
  • Distance: 2,408.1 mi
  • Duration: 2d 21h

What companies run services between Chicago, IL, USA and San Luis Obispo, CA, USA?

You can take a bus from Chicago Bus Station to San Luis Obispo Railroad Museum via St Louis Bus Station and Los Angeles Union Station in around 2d 4h.

Operators