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Chicago to San Luis Obispo buses

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Trip Overview

The average bus between Chicago and San Luis Obispo takes 3d 3h and the fastest bus takes 2d 21h. The bus runs, on average, 3 times per week from Chicago to San Luis Obispo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3d 3h
Duration
2,408 mi
Distance
$504
Average price
3 times a week
Frequency

Chicago to San Luis Obispo bus times

Buses run 3 times a week between Chicago and San Luis Obispo. The service departs Chicago at 5:05 PM in the evening, which arrives into San Luis Obispo at 13:00:00. All services require a transfer at St Louis Bus Station and take an average of 3d 3h. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

  •  → 

    Arrives +3 days

    Flixbus USAGreyhound USAFlixbus USA2d 21h • 2 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +3 days

    Flixbus USAGreyhound USAFlixbus USA2d 21h • 2 changes

Frequently asked questions

Want to know about travelling from Chicago to San Luis Obispo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago to San Luis Obispo.ExpandLaunch map view
  • Distance: 2,408.1 mi
  • Duration: 3d 3h

What companies run services between Chicago, IL, USA and San Luis Obispo, CA, USA?

You can take a bus from Chicago Bus Station to San Luis Obispo Railroad Museum via St Louis Bus Station and Los Angeles Union Station in around 2d 4h.

Operators