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Chicago to Santa Clarita buses

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Trip Overview

The average bus between Chicago and Santa Clarita takes 2d 19h and the fastest bus takes 2d 13h. The bus runs, on average, 3 times per week from Chicago to Santa Clarita. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 19h
Duration
2,249 mi
Distance
3 times a week
Frequency

Chicago to Santa Clarita bus times

Buses run 3 times a week between Chicago and Santa Clarita. The earliest departure is at 5:05 PM in the evening, and the last departure from Chicago is at 5:05 PM which arrives into Santa Clarita at 4:40 AM. All services require a transfer at St Louis Bus Station and take an average of 2d 19h. The schedules shown below are for the next available departures.

Departing Sunday, October 18, 2026

  •  → 

    Arrives +3 days

    Flixbus USAGreyhound USAAmtrak2d 13h • 2 changes

Departing Monday, October 19, 2026

  •  → 

    Arrives +3 days

    Flixbus USAGreyhound USAAmtrak2d 13h • 2 changes

Frequently asked questions

Want to know about travelling from Chicago to Santa Clarita? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago to Santa Clarita.ExpandLaunch map view
  • Distance: 2,249.3 mi
  • Duration: 2d 19h

What companies run services between Chicago, IL, USA and Santa Clarita, CA, USA?

You can take a bus from Chicago Bus Station to Santa Clarita-Newhall Amtrak Station via St Louis Bus Station, Los Angeles Union Station, and Los Angeles in around 2d 1h.

Operators