- Distance: 317.8 mi
- Duration: 6h 4m
The average bus between Chicago and St. Louis Union Station takes 6h 4m and the fastest bus takes 5h 55m. The bus service runs several times per day from Chicago to St. Louis Union Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Chicago and St. Louis Union Station. The earliest departure is at 12:15 AM at night, and the last departure from Chicago is at 5:15 PM which arrives into St. Louis Union Station at 11:20 PM. All services run direct with no transfers required, and take on average 6h 4m. The schedules shown below are for the next available departures.
Want to know about travelling from Chicago to St. Louis Union Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Chicago station and arriving at St. Louis Union Station station. Services depart 3 times a day, and operate Once daily. The journey takes approximately 6h 4m.
Chicago to St. Louis Union Station bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to St. Louis Union Station bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Book your Chicago to St. Louis Union Station bus tickets online with Flixbus USA.
The distance between Chicago and St. Louis Union Station is 422.3 km. The road distance is 511 km.
Flixbus USA operates a bus from Chicago Bus Station to St Louis Bus Station twice daily. Tickets cost $50–85 and the journey takes 5h 55m.
