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Chicago to West Lafayette, IN buses

Find Transport to West Lafayette, IN

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Trip Overview

The average bus between Chicago and West Lafayette, IN takes 5h 13m and the fastest bus takes 2h 56m. There is at least one bus per day from Chicago to West Lafayette, IN. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 13m
Duration
123 mi
Distance
$29
Average price
Once daily
Frequency

Chicago to West Lafayette, IN bus times

Buses run once daily between Chicago and West Lafayette, IN. The service departs Chicago at 10:15 AM in the morning, which arrives into West Lafayette, IN at 06:11:27. All services require a transfer at Lafayette Amtrak Station and take an average of 5h 13m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayCityBus18h 56m • 1 change

Departing Monday, November 9, 2026

  •  → 

    Amtrak ThruwayCityBus2h 56m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Amtrak ThruwayCityBus2h 56m • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    Amtrak ThruwayCityBus2h 56m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Amtrak ThruwayCityBus2h 56m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Amtrak ThruwayCityBus2h 56m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Amtrak ThruwayCityBus2h 56m • 1 change

Frequently asked questions

Want to know about travelling from Chicago to West Lafayette, IN? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago to West Lafayette, IN.ExpandLaunch map view
  • Distance: 123.3 mi
  • Duration: 5h 13m

What companies run services between Chicago, IL, USA and West Lafayette, IN, USA?

Amtrak Thruway operates a bus from Chicago Union Station to Lafayette Amtrak Station once daily. Tickets cost $23–45 and the journey takes 2h 20m.

Operators