The bus between Chicago and Winston-Salem takes 35h 40m. The bus runs, on average, once a week from Chicago to Winston-Salem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once a week between Chicago and Winston-Salem. The service departs Chicago at 9:30 PM at night, which arrives into Winston-Salem at 10:10:00. All services require a transfer, and take on average 35h 40m. The schedules shown below are for the next available departures.
Want to know about travelling from Chicago to Winston-Salem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Chicago to Winston-Salem. However, there are services departing from Chicago station and arriving at Winston-Salem station via Toledo. The journey, including transfers, takes approximately 35h 40m.
Chicago to Winston-Salem bus services, operated by Amtrak, depart from Chicago Union Station.
Chicago to Winston-Salem bus services, operated by Amtrak, arrive at Winston Salem(Trans Center) station.
Book your Chicago to Winston-Salem bus tickets online with Amtrak and Greyhound USA.
The distance between Chicago and Winston-Salem is 904.7 km. The road distance is 1,297 km.
You can take a bus from Chicago Union Station to Winston Salem(Trans Center) via Toledo Bus Stop in around 17h 58m.