The average bus between Cholula and Guadalajara takes 10h 15m and the fastest bus takes 9h 45m. The bus service runs several times per day from Cholula to Guadalajara. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Cholula and Guadalajara. The earliest departure is at 6:25 AM in the morning, and the last departure from Cholula is at 7:45 PM which arrives into Guadalajara at 5:30 AM. All services require a transfer at Mexico City Degollado and take an average of 10h 15m. The schedules shown below are for the next available departures.


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9h 55m • 2 changesWant to know about travelling from Cholula to Guadalajara? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cholula to Guadalajara. However, there are services departing from Puebla station and arriving at Nueva Central Camionera de Guadalajara Mod 1 station via Mexico City Degollado station. The journey, including transfers, takes approximately 10h 15m.
Cholula to Guadalajara bus services, operated by Flixbus USA, depart from Puebla station.
Cholula to Guadalajara bus services, operated by Primera Plus, arrive at Nueva Central Camionera de Guadalajara Mod 1 station.
The distance between Cholula and Guadalajara is 562.7 km. The road distance is 663 km.
You can take a bus from Puebla to Nueva Central Camionera de Guadalajara Mod 1 via Mexico City Degollado, Norte y Aldama, Central del Norte, and Terminal Central de Autobuses del Norte in around 10h 10m.