The average bus between Cholula and Guanajuato takes 9h 46m and the fastest bus takes 7h 10m. The bus service runs several times per day from Cholula to Guanajuato. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Cholula and Guanajuato. The earliest departure is at 12:05 AM at night, and the last departure from Cholula is at 7:30 PM which arrives into Guanajuato at 5:35 AM. All services require a transfer at Puebla, Central de Autobuses and take an average of 9h 46m. The schedules shown below are for the next available departures.

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Want to know about travelling from Cholula to Guanajuato? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cholula to Guanajuato. However, there are services departing from Cholula station and arriving at Guanajuato station via Guanajuato. The journey, including transfers, takes approximately 9h 46m.
Cholula to Guanajuato bus services, operated by Flixbus USA, depart from Puebla station.
Cholula to Guanajuato bus services, operated by Flixbus USA, arrive at Guanajuato station.
The distance between Cholula and Guanajuato is 379 km. The road distance is 472 km.
Futura operates a bus from Puebla to Guanajuato 4 times a day. Tickets cost $1,300–1,900 and the journey takes 6h 10m.