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Cincinnati to Mechanicsburg buses

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Trip Overview

The average bus between Cincinnati and Mechanicsburg takes 15h 23m and the fastest bus takes 14h 58m. The bus runs, on average, 4 times per week from Cincinnati to Mechanicsburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h 23m
Duration
521 mi
Distance
$95
Average price
4 times a week
Frequency

Cincinnati to Mechanicsburg bus times

Buses run 4 times a week between Cincinnati and Mechanicsburg. The earliest departure is at 3:00 PM in the afternoon, and the last departure from Cincinnati is at 3:00 PM which arrives into Mechanicsburg at 7:41 AM. All services require a transfer at Harrisburg Bus Station and take an average of 15h 23m. The schedules shown below are for the next available departures.

Departing Sunday, October 18, 2026

  •  → 

    Arrives next day

    Flixbus USARabbit Transit14h 58m • 1 change

Departing Monday, October 19, 2026

  •  → 

    Arrives next day

    Flixbus USARabbit Transit14h 58m • 1 change

Departing Thursday, October 22, 2026

  •  → 

    Arrives next day

    Flixbus USARabbit Transit14h 58m • 1 change

Departing Friday, October 23, 2026

  •  → 

    Arrives next day

    Flixbus USARabbit Transit16h 41m • 1 change

Frequently asked questions

Want to know about travelling from Cincinnati to Mechanicsburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Cincinnati to Mechanicsburg.ExpandLaunch map view
  • Distance: 521.1 mi
  • Duration: 15h 23m

What companies run services between Cincinnati, OH, USA and Mechanicsburg, Cumberland County, PA, USA?

Flixbus USA operates a bus from Cincinnati to Harrisburg Bus Station 5 times a week. Tickets cost $75–120 and the journey takes 10h 35m.

Operators