The average bus between Clayton and Saint Charles takes 1h 28m and the fastest bus takes 53 min. There is a bus service every few hours from Clayton to Saint Charles. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Clayton and Saint Charles. The earliest departure is at 12:33 AM at night, and the last departure from Clayton is at 9:34 PM which arrives into Saint Charles at 11:09 PM. All services require a transfer, and take on average 1h 28m. The schedules shown below are for the next available departures.

1h 36m • 1 change

1h 36m • 1 change

1h 36m • 1 change

1h 36m • 1 change

5h 15m • 1 change

56 min • 1 change

53 min • 1 change

1h 13m • 1 change

5h 16m • 1 change

56 min • 1 change

53 min • 1 change

1h 13m • 1 change
Want to know about travelling from Clayton to Saint Charles? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Clayton to Saint Charles. However, there are services departing from Clayton station and arriving at Saint Charles station via North Hanley Transit Center. The journey, including transfers, takes approximately 1h 28m.
Clayton to Saint Charles bus services, operated by Metro St. Louis, depart from North Hanley @ Maryland Nb station.
Clayton to Saint Charles bus services, operated by Metro St. Louis, arrive at 4375 Rider Trail North Sb station.
The distance between Clayton and Saint Charles is 20.8 km. The road distance is 26 km.
You can take a bus from North Hanley @ Maryland Nb to 4375 Rider Trail North Sb via North Hanley Transit Center in around 1h 6m.