The average bus between Coimbra and Santiago do Cacém takes 4h 48m and the fastest bus takes 4h 20m. The bus service runs several times per day from Coimbra to Santiago do Cacém. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Coimbra and Santiago do Cacém. The earliest departure is at 7:30 AM in the morning, and the last departure from Coimbra is at 5:00 PM which arrives into Santiago do Cacém at 9:40 PM. All services require a transfer, and take on average 4h 48m. The schedules shown below are for the next available departures.

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Want to know about travelling from Coimbra to Santiago do Cacém? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Coimbra to Santiago do Cacém. However, there are services departing from Coimbra station and arriving at Santiago do Cacém station via Estação Rodoviária de Sete Rios. The journey, including transfers, takes approximately 4h 48m.
Coimbra to Santiago do Cacém bus services, operated by Rede Expressos, depart from Terminal Rodoviário de Coimbra station.
Coimbra to Santiago do Cacém bus services, operated by Rede Expressos, arrive at Terminal Rodoviário de Santiago do Cacém station.
Book your Coimbra to Santiago do Cacém bus tickets online with Rede Expressos.
The distance between Coimbra and Santiago do Cacém is 244.5 km. The road distance is 318 km.
You can take a bus from Terminal Rodoviário de Coimbra to Terminal Rodoviário de Santiago do Cacém via Estação Rodoviária de Sete Rios in around 5h 25m.