Rome2Rio

Colorado to San Diego buses

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Trip Overview

The average bus between Colorado and San Diego takes 38h 23m and the fastest bus takes 36h 27m. The bus runs, on average, 5 times per week from Colorado to San Diego. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

38h 23m
Duration
1,120 mi
Distance
$234
Average price
5 times a week
Frequency

Colorado to San Diego bus times

Buses run 5 times a week between Colorado and San Diego. The earliest departure is at 1:07 AM at night, and the last departure from Colorado is at 10:48 AM which arrives into San Diego at 10:15 PM. All services require a transfer at 16th Street & Wewatta St and take an average of 38h 23m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Regional TransportGreyhound USAGreyhound USAFlixbus USA36h 27m • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Regional TransportGreyhound USAGreyhound USAFlixbus USA36h 27m • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Regional TransportGreyhound USAGreyhound USAFlixbus USA36h 27m • 3 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Regional TransportGreyhound USAGreyhound USAFlixbus USA36h 29m • 3 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Regional TransportGreyhound USAGreyhound USAFlixbus USA46h 8m • 3 changes

Frequently asked questions

Want to know about travelling from Colorado to San Diego? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Colorado to San Diego.ExpandLaunch map view
  • Distance: 1,120 mi
  • Duration: 38h 23m

What companies run services between Colorado, USA and San Diego, CA, USA?

You can take a bus from Civic Center Loop to San Diego via 16th Street & Wewatta St, Denver Union Station, Las Vegas Bus Terminal, and Santa Ana Bus Stop in around 25h 53m.

Operators