The average bus between Columbia and Frederick takes 25h 43m and the fastest bus takes 24h 50m. The bus service runs several times per day from Columbia to Frederick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Columbia and Frederick. The earliest departure is at 8:30 AM in the morning, and the last departure from Columbia is at 8:05 PM which arrives into Frederick at 11:35 PM. All services require a transfer at St Louis Bus Station and take an average of 25h 43m. The schedules shown below are for the next available departures.
Arrives next day


25h 50m • 2 changes
Arrives next day


27h 30m • 2 changes
Arrives next day


25h 50m • 2 changes
Arrives next day


27h 30m • 2 changes
Arrives next day


25h 50m • 2 changes
Arrives next day


27h 30m • 2 changes
Want to know about travelling from Columbia to Frederick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Columbia to Frederick. However, there are services departing from Columbia station and arriving at Frederick station via St Louis Bus Station station. The journey, including transfers, takes approximately 25h 43m.
Columbia to Frederick bus services, operated by Greyhound USA, depart from Columbia station.
Columbia to Frederick bus services, operated by Greyhound USA, arrive at Frederick Bus Station.
Book your Columbia to Frederick bus tickets online with Greyhound USA.
The distance between Columbia and Frederick is 1,285.8 km. The road distance is 1,539 km.
You can take a bus from Columbia to Frederick Bus Station via St Louis Bus Station and Pittsburgh Intermodal Station in around 23h.