- Distance: 420.5 mi
- Duration: 10h 16m
The average bus between Columbus, OH and St. Louis takes 10h 16m and the fastest bus takes 9h 5m. The bus service runs several times per day from Columbus, OH to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Columbus, OH and St. Louis. The earliest departure is at 3:40 AM at night, and the last departure from Columbus, OH is at 11:50 PM which arrives into St. Louis at 7:55 AM. All services run direct with no transfers required, and take on average 10h 16m. The schedules shown below are for the next available departures.
Want to know about travelling from Columbus, OH to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Columbus station and arriving at St Louis Bus Station. Services depart three times a day, and operate every day. The journey takes approximately 10h 20m.
Columbus, OH to St. Louis bus services, operated by Greyhound USA, depart from Columbus station.
Columbus, OH to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Book your Columbus, OH to St. Louis bus tickets online with Omio and FlixBus.
The distance between Columbus, OH and St. Louis is 637.2 km. The road distance is 671 km.
Greyhound USA operates a bus from Columbus to St Louis Bus Station 3 times a day. Tickets cost $75–120 and the journey takes 9h 5m.
