The average bus between Comiso and San Vito Lo Capo takes 9h 43m and the fastest bus takes 5h 55m. The bus service runs several times per day from Comiso to San Vito Lo Capo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Comiso and San Vito Lo Capo. The earliest departure is at 5:55 AM in the morning, and the last departure from Comiso is at 6:15 PM which arrives into San Vito Lo Capo at 9:50 AM. All services require a transfer at Palermo and take an average of 9h 43m. The schedules shown below are for the next available departures.

5h 55m • 1 change

5h 55m • 1 change
Arrives next day

20h 55m • 1 change

5h 55m • 1 change

5h 55m • 1 change
Arrives next day

15h 35m • 1 change

5h 55m • 1 change

5h 55m • 1 change
Arrives next day

15h 35m • 1 change
Want to know about travelling from Comiso to San Vito Lo Capo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Comiso to San Vito Lo Capo. However, there are services departing from Comiso station and arriving at San Vito Lo Capo station via Palermo. The journey, including transfers, takes approximately 9h 43m.
Comiso to San Vito Lo Capo bus services, operated by Azienda Siciliana Trasporti, depart from Comiso station.
Comiso to San Vito Lo Capo bus services, operated by Azienda Siciliana Trasporti, arrive at Via Piersanti Mattarella, San Vito Lo Capo station.
The distance between Comiso and San Vito Lo Capo is 213.9 km. The road distance is 327 km.
You can take a bus from Comiso to Via Piersanti Mattarella, San Vito Lo Capo via Palermo and Palermo Centrale Station in around 6h 40m.