The average bus between Comitán and Guadalajara takes 25h 20m and the fastest bus takes 24h 50m. The bus service runs several times per day from Comitán to Guadalajara. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Comitán and Guadalajara. The earliest departure is at 2:30 PM in the afternoon, and the last departure from Comitán is at 8:00 PM which arrives into Guadalajara at 8:50 PM. All services require a transfer at Balbuena and take an average of 25h 20m. The schedules shown below are for the next available departures.
Arrives next day

25h 20m • 1 change
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25h 50m • 1 change
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24h 50m • 1 change
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25h 20m • 1 change
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25h 50m • 1 change
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24h 50m • 1 change
Arrives next day

25h 20m • 1 change
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25h 50m • 1 change
Arrives next day

24h 50m • 1 change
Arrives next day

25h 20m • 1 change
Arrives next day

25h 50m • 1 change
Arrives next day

24h 50m • 1 change
Want to know about travelling from Comitán to Guadalajara? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Comitán to Guadalajara. However, there are services departing from Comitán station and arriving at Guadalajara station via Balbuena. The journey, including transfers, takes approximately 25h 20m.
Comitán to Guadalajara bus services, operated by ADO, depart from Comitán station.
Comitán to Guadalajara bus services, operated by ADO, arrive at Guadalajara Portales station.
Book your Comitán to Guadalajara bus tickets online with ADO and Primera Plus.
The distance between Comitán and Guadalajara is 1,284.5 km. The road distance is 1,492 km.
You can take a bus from Comitán to Sala 2 de la Central de Autobuses via Balbuena, Balbuena, Moctezuma, Ciudad de México Moctezuma, Guadalajara Portales, and Carlos Salgado in around 22h 26m.